Composite map of human Kv1.3 channel in apo state with beta subunits

NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE

Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.

The above mentioned 3.4 Ang resolution was obtained for TM domain after application of C4 symmetry. The soluble domain map (another map deposited here) was resolved to 2.9 Ang.

Soluble domain focused map of human Kv1.3

Potassium voltage-gated channel subfamily A member 3

Voltage-gated potassium channel subunit beta-2

HGK5,HLK3,HPCN3,Voltage-gated K(+) channel HuKIII,Voltage-gated potassium channel subunit Kv1.3

K(+) channel subunit beta-2,Kv-beta-2,hKvbeta2

Human Kv1.3 channel in apo condition in complex with beta subunits

Ion channel, Kv channel, Potassium channel, Peptide toxin, ShK, Dalazatide, Selectivity filter, Molecular dynamics simulation, MEMBRANE PROTEIN