Drosophila Melanogaster (6-4) Photolyase Bound To double stranded Dna containing a T(6-4)C Photolesion

5-aminothymidine 5'-(dihydrogen phosphate)

Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of Uv- Induced (6-4) and Dewar Photolesions.

Crystal Structure and Mechanism of a DNA (6-4) Photolyase.

6-4 LINK BETWEEN T 8 AND C 8 (SEE REMARK 600)
5'-D(*AP*CP*AP*GP*CP*GP*GP*64PP*ZP*GP*CP*AP *GP*GP*T)-3'

PROTEIN WAS MIXED WITH DNA IN A 1:1.1 MOLAR RATIO WITH A FINAL CONCENTRATION OF 8.5MG/ML PROTEIN. 0.1M HEPES PH 7, 15-20% POLYETHYLENGLYCOL 4000, HANGING-DROP VAPOUR DIFFUSION

CHAIN C HETEROGENS 64P AND Z:
RESIDUES DT 8 AND DC 9 HAVE FORMED A PHOTOPRODUCT BY THE
COVALENT BONDING OF ATOM C6 OF 64P TO C4 OF Z.

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES RESIDUAL ONLY

LYASE-DNA COMPLEX, PHOTOLESION, DNA PHOTOLYASE, LYASE