CRYSTAL STRUCTURE OF THE ADCC-POTENT, WEAKLY NEUTRALIZING HIV ENV CO-RECEPTOR BINDING SITE ANTIBODY N12-I2 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 AND M48U1

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site.

ANTI-HIV ANTIBODY N12-I2 FAB LIGHT CHAIN

ANTI-HIV ANTIBODY N12-I2 FAB HEAVY CHAIN

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

clade A/E 93TH057 HIV-1 gp120 core, FAB FRAGMENT OF HUMAN ANTI-HIV ANTIBODY N12-I2, LIGHT CHAIN, FAB FRAGMENT OF HUMAN ANTI-HIV ANTIBODY N12-I2, HEAVY CHAIN, M48U1 CD4 MIMETIC PEPTIDE

ADCC AND NEUTRALIZING ANTI-HIV-1 ENV ANTIBODY N12-I2, CD4I ANTIBODY, FAB FRAGMENT, HIV-1 GP120, IMMUNE SYSTEM, CLADE A/E 93TH057, VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX