Crystal structure of human TLR8 in complex with Resiquimod (R848) crystal form 1

Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

14%(w/v) PEG3350, 0.1M MES, 0.15M ammonium sulfate, pH 5.2, VAPOR DIFFUSION, SITTING DROP, temperature 293K

Leucine Rich Repeat, RNA, Glycosylation, RNA Recognition, ssRNA, Receptor, RNA Receptor, Innate Immunity, RNA Binding, Secreted, Resiquimod, Antivirus and Antitumor Drug, Antivirus and Antitumor Drug Binding, IMMUNE SYSTEM