Structure of Neuraminidase from English duck subtype N6 complexed with 30 mM sialic acid (NANA, Neu5Ac), crystal soaked for 3 hours at 291 K

The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites

INFLUENZA VIRUS GROWN IN EMBRIONATED CHICKEN EGG

COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 5 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE

INFLUENZA VIRUS B/BEIJING/1/87 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR

INFLUENZA VIRUS B/BEIJING/1/87 NEURAMINIDASE COMPLEXED WITH DIHYDROPYRAN-PHENETHYL-PROPYL- CARBOXAMIDE

NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE

NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN TEH ACTIVE SITE

THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH THE GLAXO 6-CARBOXAMIDE SIALIC ACID ANALOGUE GR217029

STRUCTURE OF THE MULTIFUNCTIONAL PARAMYXOVIRUS HEMAGGLUTININ-NEURAMINIDASE

SIALIDASE OR NEURAMINIDASE, LARGE 68KD FORM

NATIVE INFLUENZA VIRUS NEURAMINIDASE IN COMPLEX WITHNEU5AC2EN

NATIVE INFLUENZA NEURAMINIDASE IN COMPLEX WITH 4-AMINO-2-DEOXY-2,3-DEHYDRO-N- NEURAMINIC ACID

NATIVE INFLUENZA NEURAMINIDASE IN COMPLEX WITH 9-AMINO-2-DEOXY-2,3-DEHYDRO-N- NEURAMINIC ACID

NATIVE INFLUENZA NEURAMINIDASE IN COMPLEX WITH 4,9-DIAMINO-2-DEOXY-2,3-DEHYDRO-N- ACETYL-NEURAMINIC ACID

INFLUENZA VIRUS B/LEE/40 NEURAMINIDASE COMPLEXED WITH BANA113 INHIBITOR

INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA109 INHIBITOR

INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA111 INHIBITOR

INFLUENZA B/LEE/40 NEURAMINIDASE (SIALIDASE) COMPLEXED WITH EPANA INHIBITOR (4-ACETAMIDO- 2,4-DIDEOXY-D-GLYCERO-ALPHA-D-GALACTO-1 -OCTOPYRANOSYL) PHOSPHONIC ACID

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH APANA INHIBITOR (4- ACETAMIDO- 2,4-DIDEOXY-D-GLYCERO-BETA-D- GALACTO-1-OCTOPYRANOSYL) PHOSPHONIC ACID

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH EPANA INHIBITOR (4- ACETAMIDO- 2,4-DIDEOXY-D-GLYCERO-ALPHA-D- GALACTO-1-OCTOPYRANOSYL) PHOSPHONIC ACID

INFLUENZA A SUBTYPE N9 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH EPANA INHIBITOR (4- ACETAMIDO- 2,4-DIDEOXY-D-GLYCERO-ALPHA-D- GALACTO-1-OCTOPYRANOSYL) PHOSPHONIC ACID

INFLUENZA VIRUS B/LEE/40 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH BANA105 INHIBITOR (4 -(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID )

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH AROMATIC BANA106 INHIBITOR (4-(ACETYLAMINO)-5-AMINO-3- HYDROXYBENZOIC ACID)

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH AROMATIC BANA105 INHIBITOR (4-(ACETYLAMINO)-3-HYDROXY-5- NITROBENZOIC ACID)

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH AROMATIC BANA108 INHIBITOR (4-(ACETYLAMINO)-3-AMINOBENZOIC ACID )

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE) COMPLEXED WITH DANA INHIBITOR (2- DEOXY-2,3-DIDEHYDRO-D-N-ACETYLNEURAMINIC ACID)

INFLUENZA A SUBTYPE N2 NEURAMINIDASE ( SIALIDASE)

CRYSTAL STRUCTURE OF INFLUENZA VIRUS NEURAMINIDASE INCOMPLEX WITH BCX-1812

CRYSTAL STRUCTURE OF E119G MUTANT INFLUENZA VIRUSNEURAMINIDASE IN COMPLEX WITH BCX-1812

CRYSTAL STRUCTURE OF R292K MUTANT INFLUENZA VIRUSNEURAMINIDASE IN COMPLEX WITH BCX-1812

THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE

N9 NEURAMINIDASE-NC41 MUTANT WITH ASN 329 REPLACED BY ASP (N329D) COMPLEX WITH FAB

N9 NEURAMINIDASE-NC41 MUTANT WITH ILE 368 REPLACED BY ARG (I368R) COMPLEX WITH FAB

MOL_ID: 1; MOLECULE: N9 NEURAMINIDASE; CHAIN : N; EC: 3.2.1.18; MUTATION: WILD TYPE ; MOL_ID: 2; MOLECULE: FAB NC10; CHAIN: L , H; OTHER_DETAILS: RESOLUTION OF 3.0 ANGSTROMS

MOL_ID: 1; MOLECULE: N9 NEURAMINIDASE; CHAIN : N; EC: 3.2.1.18; MUTATION: WILD TYPE ; MOL_ID: 2; MOLECULE: FAB NC10; CHAIN: L , H; OTHER_DETAILS: RESOLUTION OF 2.5 ANGSTROMS

COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE

NEURAMINIDASE (SIALIDASE) COMPLEXED WITH 2- DEOXY-2,3-DEHYDRO-N-ACETYL NEURAMINIC ACID

INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN ) COMPLEXED WITH 4-GUANIDINO-NEU5AC2EN INHIBITOR

NEURAMINIDASE (SIALIDASE) COMPLEX WITH N- ACETYL NEURAMINIC ACID (SIALIC ACID)

NEURAMINIDASE (SIALIDASE) COMPLEX WITH 2,3- DEHYDRO-2-DEOXY-N-ACETYL NEURAMINIC ACID ( DANA)

NEWCASTLE DISEASE VIRUS HEMAGGLUTININ- NEURAMINIDASE COMPLEXED WITH THIOSIALOSIDE

CRYSTAL STRUCTURE OF THE NEWCASTLE DISEASE VIRUS HEMAGGLUTININ-NEURAMINIDASE COMPLEXED WITH THIOSIALOSIDE

STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMANPARAINFLUENZA VIRUS TYPE III

STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMANPARAINFLUENZA VIRUS TYPE III: COMPLEX WITH NEU5AC

STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMANPARAINFLUENZA VIRUS TYPE III: COMPLEX WITH NEU5AC2EN

STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMANPARAINFLUENZA VIRUS TYPE III: COMPLEX WITH ZANAMAVIR

INFLUENZA B VIRUS NEURAMINIDASE COMPLEXED WITH 1-(4-CARBOXY-2-(3-PENTYLAMINO)PHENYL)-5 -AMINOMETHYL-5-HYDROXYMETHYL-PYRROLIDIN-2-ONE

STRUCTURE OF NEURAMINIDASE FROM ENGLISH DUCK SUBTYPE N6 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 3 HOURS AT 277 K.

STRUCTURE OF NEURAMINIDASE FROM ENGLISH DUCK SUBTYPE N6 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 43 HOURS AT 291 K.

STRUCTURE OF NEURAMINIDASE FROM ENGLISH DUCK SUBTYPE N6.

CONTRIBUTION OF THE ACTIVE SITE ASPARTIC ACID TO CATALYSIS IN THE BACTERIAL NEURAMINIDASE FROM MICROMONOSPORA VIRIDIFACIENS.

N9 TERN INFLUENZA NEURAMINIDASE COMPLEXED WITH (2R,4R,5R)-5-(1-ACETYLAMINO-3-METHYL- BUTYL-PYRROLIDINE-2, 4-DICAROBYXYLIC ACID 4 -METHYL ESTERDASE COMPLEXED WITH

N9 TERN INFLUENZA NEURAMINIDASE COMPLEXED WITH A 2,5-DISUBSTITUTED TETRAHYDROFURAN-5- CARBOXYLIC ACID

PARAINFLUENZA VIRUS 5 (SV5) HEMAGGLUTININ- NEURAMINIDASE(HN) WITH LIGAND DANA (SOAKED WITH DANA, PH 7.0)

PARAINFLUENZA VIRUS 5 (SV5) HEMAGGLUTININ- NEURAMINIDASE(HN) WITH LIGAND DANA (SOAKED WITH DANA, PH8.0)

PARAINFLUENZA VIRUS 5 (SV5) HEMAGGLUTININ- NEURAMINIDASE(HN) WITH LIGAND SIALYLLACTOSE ( SOAKED WITH SIALYLLACTOSE,PH8.0)

PARAINFLUENZA VIRUS 5 (SV5) HEMAGGLUTININ- NEURAMINIDASE(HN) (PH 8.0)

PARAINFLUENZA VIRUS 5 (SV5) HEMAGGLUTININ- NEURAMINIDASE(HN) WITH LIGAND DANA(SOAKED WITH SIALIC ACID, PH7.0))

PARAINFLUENZA VIRUS 5 (SV5) HEMAGGLUTININ- NEURAMINIDASE(HN) WITH LIGAND DANA (SOAKED WITH SIALIC ACID, PH 8.0)

NEURAMINIDASE N2 COMPLEX WITH SIALIC ACID (N -ACTYL NEURAMINIC ACID)

THE X-RAY STRUCTURE OF A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF SIALIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF NEU5AC2EN AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF 4- AMINO-NEU5AC2EN AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF 4- GUANIDINO-NEU5AC2EN AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF N- ACETYL-4-GUANIDINO-6- METHYL(PROPYL) CARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2- CARBOXYLIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF 5- N-ACETYL-4-AMINO-6- DIETHYLCARBOXAMIDE-4,5 -DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF 5- N-ACETYL-5-AMINO-3- (1-ETHYLPROPOXY)-1- CYCLOHEXENE-1-CARBOXYLIC ACID (GS4071) AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF N- ACETYL-4-GUANIDINO-6- METHYL(PROPYL) CARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2- CARBOXYLIC ACID AND WILDTYPE TERN N9 INFLUENZA VIRUS NEURAMINIDASE

THE X-RAY STRUCTURE OF A COMPLEX OF 5- N-ACETYL-5-AMINO-3- (1-ETHYLPROPOXY)-1- CYCLOHEXENE-1-CARBOXYLIC ACID (GS4071) AND WILDTYPE TERN N9 INFLUENZA VIRUS NEURAMINIDASE

NEURAMINIDASE N9 (SIALIDASE) (MUTANT WITH ASN 329 REPLACED BY ASP) (N329D)

NEURAMINIDASE N9 (SIALIDASE) (MUTANT WITH ILE 368 REPLACED BY ARG) (I368R)

NEURAMINIDASE N9 (SIALIDASE) (MUTANT WITH ALA 369 REPLACED BY ASP) (A369D)

NEURAMINIDASE N9 (SIALIDASE) (MUTANT WITH LYS 432 REPLACED BY ASN) (K432N)

NATIVE INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN)

UNLIKE OTHER VIRAL NEURAMINIDASES SOLVED TO DATE, N6 HAS A FULL TETRAMER IN THE ASYMMETRIC UNIT

INFLUENZA TYPE A, NEURAMINIDASE, HB SITE, SIALIC ACID, SUBTYPE N6, HYDROLASE