Structure of human neuronal nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.

Constitutive NOS,NC-NOS,NOS type I,Neuronal NOS,nNOS,Peptidyl-cysteine S-nitrosylase NOS1,bNOS

8% PEG3350
35mM citric acid
65mM Bis-Tris-Propane
10% glycerol
5mM TCEP

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Nitric oxide synthase, brain (E.C.1.14.13.39)

nitric oxide synthase inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex