Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-(2-(((2-Aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.

neuronal nitric oxide synthase, BNOS, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, nNOS, Peptidyl-cysteine S-nitrosylase NOS1

20-24% PEG3350, 0.1 M MES, 0.14-0.20 M ammonium acetate, 10% ethylene glycol, 30 uM SDS, 5 mM GSH

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Reflection file was treated with the diffraction anisotropy correction. (https://services.mbi.ucla.edu/anisoscale/).

Nitric oxide synthase, brain (E.C.1.14.13.39)

nitric oxide synthase, inhibitor complex, heme enzyme, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex