Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state

PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER

The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.

Microtubule-bound KLP61F motor in the AMPPNP state

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

National Science Foundation (NSF, United States)

Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state

Tubulin alpha-1A chain, Tubulin beta chain, Kinesin-like protein Klp61F

Kinesin-5, microtubules, mitotic spindles, AMPPNP state, cell cycle, MOTOR PROTEIN