Crystal structure of macaque anti-HIV-1 antibody RM20E1

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.

The RM20E1 Fab was crystallized from a solution containing 6.3 mg/mL protein in 1X TBS with a well solution containing 0.1M glycine, pH 10.5, 1.2M NaH2PO4, 0.8M Na2HPO4, and 0.2M Li2SO4, with 15% ethylene glycol supplemented as cryoprotectant.

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

RM20E1 Fab heavy chain, RM20E1 Fab light chain

HIV, antibody, non-human primates, IMMUNE SYSTEM