X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter

X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway.

Residue D ALA 96 and Residue D THR 97 that are next to each other in the sample sequence are not properly linked: distance between C and N is 1.20.

DNA-directed RNA polymerase subunit alpha

DNA-directed RNA polymerase subunit beta

DNA-directed RNA polymerase subunit beta'

DNA-directed RNA polymerase subunit omega

DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3')

DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*CP*C)-3')

RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha

RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta

RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'

RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', DNA-directed RNA polymerase subunit omega, RNA polymerase sigma factor SigA/DNA Complex
Thermus thermophilus, RNA polymerase, reiterative transcription, holoenzyme, transcription-DNA-RNA complex
binding site for Di-nucleotide GTP I 1 and G I 2