Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.

Proprotein convertase subtilisin/kexin type 9

catalytic and cysteine-rich domains, residues 153-692

Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9

Department of Energy (DOE, United States)

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Proprotein convertase subtilisin/kexin type 9, (E.C.3.4.21.-), Fab33 heavy chain, Fab33 light chain

immunoglobulin proprotein convertase, subtilisin, HYDROLASE