Crystal structure of the STX2a complexed with RRA peptide

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin.

stxII, stx2B, stx2B_2, stx2dB, stx2vB, stxB2, vtx2B

4 M Sodium Formate, 100mM MES pH 6.5, 50 mM PPS

Japan Agency for Medical Research and Development (AMED)