Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90, bound to a scaffolded WITO V1V2 domain

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.

27% isopropanol, 0.1M imidazole pH 6.5 and 10% PEG8000 were flash-frozen in liquid nitrogen in mother liquor supplemented with 20% 2-methyl-2,4-pentanedial (MPD).

VRC38.01 Heavy Chain, VRC38.01 Light Chain

Fab, HIV-1, V1V2, Env, Antibody, Envelope, Neutralizing, IMMUNE SYSTEM, WITO, 1FD6, Viral protein-IMMUNE SYSTEM complex