Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6

Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.

20% (w/v) PEG3350, 0.2M di-ammonium hydrogen citrate

Gel filtration on HiLoad Superdex200 16/60 in 20mM Hepes pH 7.4, 150mM NaCl.

anti-CDH6 Fab heavy chain,anti-CDH6 Fab heavy chain, anti-CDH6 Fab light chain,anti-CDH6 Fab light chain, Cadherin-6

antibody, cell adhesion, antibody-drug conjugate, cancer, IMMUNE SYSTEM