TcrPDEC1 catalytic domain in complex with inhibitor wyq16

propan-2-yl {[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]sulfonyl}carbamate

Cyclic nucleotide specific phosphodiesterase

The catalytic domain of the unliganded TcrPDEC1 (270-614) complex with wyq16 were crystallized by vapor diffusion against a well buffer of 20% PEG3350, 0.4 M Na formate, 0.2 M guanidine, 0.1 M MES pH 6.5 at 4oC., VAPOR DIFFUSION, HANGING DROP, temperature 277K

Cyclic nucleotide specific phosphodiesterase (E.C.3.1.4.17)

trypanosoma PDE parasite, hydrolase-hydrolase inhibitor complex