Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) in complex with an ezetimibe analog

4-[(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(4-{3-[(methylsulfonyl)amino]prop-1-yn-1-yl}phenyl)-4-oxoazetidin-2-yl]phenyl beta-D-glucopyranosiduronic acid

Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition

NPC1-like intracellular cholesterol transporter 1 (NPC1L1) in complex with an inhibitor

NPC1-like intracellular cholesterol transporter 1

Cholesterol, Transporter, Tunnel, Inhibitor, Ezetimibe, LIPID TRANSPORT-INHIBITOR complex