DNA polymerase beta product complex with 8-oxoG:A and inserted dCTP

Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.

DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')

DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG)P*C)-3')

50 mM imidazole, 350 mM sodium acetate, 17% PEG3350

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

transferase ligase / DNA, TRANSFERASE-DNA, LIGASE-DNA complex