Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 8-(2-(3-morpholino-3-oxopropoxy)phenoxy)indolizine-2-carbonitrile (JLJ757), a non-nucleoside inhibitor

Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase.

50 mM Imidazole pH 6.8, 15% PEG 8000, 100 mM ammonium sulfate, 15 mM magnesium sulfate, and 5 mM spermine

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

REVERSE TRANSCRIPTASE, ANTIVIRAL, DRUG DESIGN, HIV-1, VIRAL PROTEIN