Crystal structure of Anti-Heroin Antibody HY4-1F9 Fab Complexed with Morphine

MORPHINE; (5A,6A)-7,8-DIDEHYDRO-4,5-EPOXY-17-METHYLMORPHINIAN-3,6-DIOL; MORPHIUM; MORPHIA; DOLCONTIN; DUROMORPH; MORPHINA; NEPENTHE

Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.

20% PEG 8000
0.1M Sodium Cacodylate
0.2M Magnesium Acetate
2.25% Xylitol

National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA)