Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and GSK2-bound form

Center for Structural Genomics of Infectious Diseases (CSGID)

4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID

2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID

Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase.

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Center for Structural Genomics of Infectious Diseases
NIAID, National Institute of Allergy and Infectious Diseases

Global Health Innovative Technology Fund

Tryptophan synthase alpha chain (E.C.4.2.1.20), Tryptophan synthase beta chain (E.C.4.2.1.20)
PLP, HETEROTETRAMER, AMINO ACID BIOSYNTHESIS, SUBSTRATE CHANNELING, LYASE-LYASE INHIBITOR COMPLEX, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID