X-ray crystal structure of JRD-SIK1/2i-3 bound to a MARK2-SIK2 chimera

Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation.

ELKL motif kinase 1,EMK-1,MAP/microtubule affinity-regulating kinase 2,PAR1 homolog,PAR1 homolog b,Par-1b,Par1b

Kinase, enzyme, chimera, inhibitor, BIOSYNTHETIC PROTEIN