Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftaroline

Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus.

8 mM Zinc chloride, 80 mM sodium acetate pH 5, 100 mM sodium fluoride, and 16% polyethylene glycol 6000

Canadian Institutes of Health Research (CIHR)

Monomer as determined by size exclusion chromatography

Hydrolase, Penicillin binding protein, beta-lactam antibiotics, HYDROLASE - Antibiotic complex