X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with memantine

The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine.

200 mM ammonium sulphate, 50 mM ADA, pH 5.5, 20 % PEG 4000

ELIC, LGIC, cys-loop, channel, memantine, pore blocker, transport protein