Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP and GDP

A nucleotide-controlled conformational switch modulates the activity of eukaryotic IMP dehydrogenases.

0.1 M Lithium Acetate
0.1 M BisTris, pH 6.0
20% (w/v) Sokolan CP42

Inosine-5'-monophosphate dehydrogenase (E.C.1.1.1.205)

IMP dehydrogenase, Ashbya gossypii, allosteric modulator, purine nucleotides, Oxidoreductase