CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2

Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.

RELION autorefinement. Unmasked resolution is 3.12. After masking to remove the detergent micelle resolution is 2.96A

Detergent (UDM) purified in presence of lipid PI(4,5)P2

Images were corrected for local motion using patch-based methods with MotionCor2

Autosomal dominant polycystic kidney disease type II protein,Polycystic kidney disease 2 protein,Polycystwin,R48321,Transient receptor potential cation channel subfamily P member 2

ION CHANNEL, TRANSIENT RECEPTOR POTENTIAL CHANNEL, POLYCYSTIC KIDNEY DISEASE, Structural Genomics, Structural Genomics Consortium, SGC, MEMBRANE PROTEIN