Discovery of triazole aminopyrazines as a highly potent and selective series of PI3K delta inhibitors.

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta

50% ethylene glycol/PEG 8000, 0.1 M carboxylic acids mix, 0.1 M Buffer system 2 pH 7.5

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (E.C.2.7.1.153)