Crystal structure of CAB1 Pantothenate Kinase from Saccharomyces cerevisiae in complex with compound YU281445

High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development.

Coenzyme A biosynthesis protein 1,Pantothenic acid kinase CAB1

0.18 M Sodium fluoride, 20% w/v PEG 3350

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

kinase, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex