Co-crystal structure of SV40 large T antigen helicase domain and ADP

Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.

Tris, magnesium chloride, PEG 8000, DTT, pH 7.25, VAPOR DIFFUSION, HANGING DROP, temperature 277K

The biological hexamer is generated from 2 asu related by crystallgraphic 2-fold axis.