Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex

Architecture of human Rag GTPase heterodimers and their complex with mTORC1.

RagA,Adenovirus E3 14.7 kDa-interacting protein 1,FIP-1

RagC,GTPase-interacting protein 2,TIB929

100mM MOPSO, Bis-Tris pH 6.5, 40mM polyamines ( mixture of spermine tetrahydrochloride, spermidine trihydrochloride, 1,4. diaminobutane dihydrochloride, 0.1 M D/L-ornithine monohydrochloride), 10% (w/v) PEG 8000. 20% (v/v) 1,5 - Pentanediol and 24 % (v/v) glycerol.

Medical Research Council (United Kingdom)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : WITH TLS ADDED

Ras-related GTP-binding protein A, Ras-related GTP-binding protein C

small GTPases, mTORC1 activator, roadblock domain, GTPase domain, SIGNALING PROTEIN