OXA-48 in complex with Avibactam at pH 6.5

avibactam, bound form, NXL104, bound form

Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition.

1.8 M (NH4)2SO4, 0.1 M MES pH 6.5, 10 mM CoCl2, 2mM avibactam, VAPOR DIFFUSION, SITTING DROP, temperature 298.15K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

This protein behaves as a dimer in solution