Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and inhibitor imido-diphosphate (PNP)

Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.

S-adenosylmethionine synthase isoform type-2

AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II

100 mM ammonium citrate and 12% PEG-3350

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

National Institutes of Health/National Cancer Institute (NIH/NCI)

Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and inhibitor, di-imido triphosphate (PNPNP)

SAM SYNTHETASE, ENZYME MECHANISM, INHIBITOR, TRANSITION STATE, TRANSFERASE-INHIBITOR COMPLEX, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex