T. Brucei Farnesyl Diphosphate Synthase Complexed with Homorisedronate BPH-6

[1-hydroxy-3-(pyridin-3-yl)propane-1,1-diyl]bis(phosphonic acid)

Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.

10% MPD, 0.1 AMMONIUM ACETATE, pH 5.75, VAPOR DIFFUSION, HANGING DROP, temperature 298K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY