Cryo-EM structure of St1Cas9-sgRNA-AcrIIA6-tDNA59-ntPAM complex.

Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.

in vitro transcription vector pT7-Fluc(deltai

in vitro transcription vector pT7-Fluc(deltai)

EMDB-4900 contains AcrIIA6 bound to St1Cas9-sgRNA-tDNA20 in monomeric form

Atomic model built and refine on EMD-4900

EMDB-4901 contains AcrIIA6 bound to St1Cas9-sgRNA-tDNA20 in dimeric form

Atomic model built and refine on EMD-4901

EMDB-4902 contains St1Cas9-sgRNA-tDNA59-ntPAM proteins

Atomic model built and refine on EMD-4902

AcrIIA6, Streptococcus thermophilus DGCC 7710/RNA Complex

CRISPR-Cas9, anti-CRISPR protein, bacteriophages, Streptococcus thermophilus Cas9, St1Cas9, hydrolase