Crystal Structure Analysis of S.epidermidis adhesin SdrG binding to Fibrinogen (adhesin-ligand complex)

A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen

PEG 2000 MME, NaCl, MES, Pipes, Cacodylate, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298K

THE PEPTIDE WAS CHEMICALLY SYNTHESIZED. THE SEQUENCE OF THE PEPTIDE (NEEGFFFSARGHRPLD) IS HOMOLOGOUS TO HUMAN FIBRINOGEN B BETA CHAIN 6-20

fibrinogen-binding protein SdrG, fibrinopeptide B

SdrG, MSCRAMM-ligand complex, SdrG-fibrinopeptide complex, CELL ADHESION