ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-1

PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
ATP-GAMMA-S; ADENOSINE 5'-(3-THIOTRIPHOSPHATE); ADENOSINE 5'-(GAMMA-THIOTRIPHOSPHATE); ADENOSINE-5'-DIPHOSPHATE MONOTHIOPHOSPHATE

Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.

ClpB-DWB-K476C bound to casein in presence of ATPgammaS

same complex - middle domain conformation 1

same complex - middle domain conformation 2

disaggregase, proteostasis, AAA, CHAPERONE
binding site for Di-peptide AGS D 901 and ARG C 332
binding site for Di-peptide AGS D 901 and GLY D 211
binding site for Di-peptide AGS D 902 and THR D 607
binding site for Di-peptide AGS E 1002 and VAL E 609
binding site for Di-peptide AGS E 1002 and LYS E 611
binding site for Di-peptide AGS E 1002 and ILE E 571
binding site for Di-peptide ADP F 1001 and VAL F 210
binding site for Di-peptide ADP F 1001 and GLY F 211
binding site for Di-peptide ADP F 1001 and VAL F 180