Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP

Structural Insight into AMPK Regulation: ADP Comes into Play.

6-10% PEG 3350, 0.1M sodium citrate, pH 5.5, 5mM ADP, VAPOR DIFFUSION, HANGING DROP, temperature 293K

AMP-activated protein kinase in complex with ADP and AMP

AMP-activated protein kinase in complex with ADP and ATP

AMP-activated protein kinase in complex with AMZ

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

SNF1-like protein kinase ssp2 (E.C.2.7.11.1), SPCC1919.03c protein, AMP-activated protein kinase gamma subunit

The biological unit is a heterotrimer (There are two such trimers: A+B+G and C+D+E in the asymmetric unit), and the dimer of these heterotrimers is also physiologically relevant.

AMPK, ADP, ATP-binding, Kinase, Nucleotide-binding, Serine/threonine-protein kinase, Transferase, CBS domain