Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides

Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.

HLA class I histocompatibility antigen, A-2 alpha chain

Melanoma antigen recognized by T-cells 1 marker peptide

MART-1, Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A

0.1 M Sodium Cacodylate, pH 6.5, 15% PEG 4000, 15% Glycerol, VAPOR DIFFUSION, SITTING DROP, temperature 291K

HLA-A2 carrying ELAGIGILTV heteroclitic peptide in complex with Mel5c TCR

HLA-A2 carrying ELAGIGILTV heteroclitic peptide in complex with high affinity TCR

A sequence that occurs in cancerous melanoma cells

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Melanoma antigen recognized by T-cells 1 marker peptide, Mel5 TCR chain alpha, Mel5 TCR chain beta

Immunoglobulin, HLA, TCR, Melanoma, Immune System