Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design.

MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2

0.2M (NH4)2SO4
34% MPEG 2000
0.02M Mercaptoethanol
0.1M pH=7.2 HEPES/NaOH

Mitogen-activated protein kinase 1 (E.C.2.7.11.24)

Ser/Thr kinase, signal transduction, ATP binding, SIGNALING PROTEIN