Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PF-06840003 in Active Site and Exo site

Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase.

TDO,Tryptamin 2,3-dioxygenase,Tryptophan oxygenase,TRPO,Tryptophan pyrrolase,Tryptophanase

50 mM Sodium Citrate (pH 5.6),
2% Tacsimate (pH 5.0)
5% PEG 3350

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

National Science Foundation (NSF, United States)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

Tryptophan 2,3-dioxygenase (E.C.1.13.11.11)

Tryptophan Dioxygenase, PF-06840003, Oxidoreductase, OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex