PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 198)

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.

JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D

28% PEG3350 -- 0.1M HEPES pH 7.0 -- 0.25M ammonium sulfate

Jmjc domain of human JMJD2D screened against the ZENOBIA Fragment Library by X-ray Crystallography. Check out the PanDDA event maps at https://zenodo.org/record/290220/files/0_index.html
PanDDA analysis group deposition of models of ground state datasets

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

PanDDA, SGC - Diamond I04-1 fragment screening, Jmj domain, epigenetics, OXIDOREDUCTASE