Crystal structure of CDK4 in complex with CyclinD1 and P21

p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.

B-cell lymphoma 1 protein,BCL-1,BCL-1 oncogene,PRAD1 oncogene

CDK-interacting protein 1,Melanoma differentiation-associated protein 6,MDA-6,p21

CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1

National Institutes of Health/National Cancer Institute (NIH/NCI)

G1/S-specific cyclin-D1, Cyclin-dependent kinase 4 (E.C.2.7.11.22), Cyclin-dependent kinase inhibitor 1

Cyclin-dependent kinase, kinase inhibitor, CELL CYCLE, transferase