Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine

Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1.

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

DDAH-1, Dimethylarginine dimethylaminohydrolase 1, DDAHI, Dimethylargininase-1

20% polyethyleneglycol 6000, 0.1 M Tris-HCl, pH 8.2, VAPOR DIFFUSION, SITTING DROP, temperature 277K

human DDAH-1 bound with N5-(1-iminopropyl)-L-ornithine

human DDAH-1 bound with N5-(1-iminopentyl)-L-ornithine

IN LINKING N5-(1-IMINOPENTYL)-L-ORNITHINE TO CYS 274 THE HYBRIDIZATION STATE OF CZ CHANGES FROM SP2 TO SP3

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (E.C.3.5.3.18)

DDAH, NITRIC OXIDE SYNTHASE REGULATION, HYDROLASE-HYDROLASE INHIBITOR complex