Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state

Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.

Fusion of maltose-binding protein and voltage-gated sodium channel NavAb in the resting state

Movie frames were aligned and 2x binned to a pixel size off 1.056 A using MotionCor2.

Auto-particle picking using RELION 3.0 beta and manual particle removals of bad particles.

Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb

National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)

National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Sugar ABC transporter substrate-binding protein
Ion channel, ion transport protein, MEMBRANE PROTEIN, metal transport