Escherichia coli tRNA synthetase in complex with compound 3

Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase.

Phenylalanine--tRNA ligase alpha subunit

Phenylalanyl-tRNA synthetase alpha subunit,PheRS

Phenylalanyl-tRNA synthetase beta subunit,PheRS

Escherichia coli str. K-12 substr. MG1655

15% PEG 8,000, 200 mM MgCl2, 100 mM Tris-HCl pH 8.5, 2% 1,6-hexanediol, 3% D-Galactose

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

Phenylalanine--tRNA ligase alpha subunit (E.C.6.1.1.20), Phenylalanine--tRNA ligase beta subunit (E.C.6.1.1.20)

Inhibitor, Aminoacyl-tRNA synthetase, PheRS, Antibacterial, LIGASE