Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with S-SerMe-ImmH phosphonate

[(3S)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid

Acyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine Phosphoribosyltransferase.

Hypoxanthine-guanine-xanthine phosphoribosyltransferase

200mM sodium citrate, 20% PEG3350, pH 7.4, vapor diffusion, sitting drop, temperature 291K

Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with hypoxanthine

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Hypoxanthine-guanine-xanthine phosphoribosyltransferase (E.C.2.4.2.-)

hypoxanthine, TRANSFERASE-TRANSFERASE INHIBITOR complex