Structural basis for the mechanism and antagonism of receptor signaling mediated by Interleukin-9 (IL-9)

IL-9,Cytokine P40,T-cell growth factor P40

0.1 M ammonium sulfate, 0.1 M TRIS, pH 5.6, 18% PEG 1500

(chain A and (resid 53 through 69 or resid 78 through 90 or resid 92 through 98 or resid 102 through 125 or resid 133 through 210 or resid 218 through 229 or resid 241 through 256))

(chain C and (resid 53 through 69 or resid 78 through 90 or resid 92 through 98 or resid 102 through 125 or resid 133 through 210 or resid 218 through 229 or resid 241 through 256))

(chain G and (resid 53 through 69 or resid 78 through 90 or resid 92 through 98 or resid 102 through 125 or resid 133 through 210 or resid 218 through 229 or resid 241 through 256))

(chain I and (resid 53 through 125 or resid 133 through 210 or resid 218 through 229 or resid 241 through 256))

(chain K and (resid 53 through 69 or resid 78 through 90 or resid 92 through 98 or resid 102 through 125 or resid 133 through 210 or resid 218 through 256))

(chain M and (resid 53 through 69 or resid 78 through 90 or resid 92 through 98 or resid 102 through 125 or resid 133 through 210 or resid 218 through 229 or resid 241 through 256))

(chain O and (resid 53 through 69 or resid 78 through 90 or resid 92 through 98 or resid 102 through 210 or resid 218 through 229 or resid 241 through 256))

(chain B and (resid 20 through 60 or resid 67 through 113 or resid 116 through 138))

(chain D and (resid 20 through 113 or resid 116 through 138))

(chain F and (resid 20 through 60 or resid 67 through 113 or resid 116 through 138))

(chain H and (resid 20 through 60 or resid 67 through 113 or resid 116 through 138))

(chain J and (resid 20 through 60 or resid 67 through 113 or resid 116 through 138))

(chain L and (resid 20 through 60 or resid 67 through 113 or resid 116 through 138))

(chain N and (resid 20 through 60 or resid 67 through 113 or resid 116 through 138))

(chain P and (resid 20 through 60 or resid 67 through 138))