Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11b

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs.

Hydrogens have been added in their riding positions

Cereblon, PROTAC, E3, molecular glue, SIGNALING PROTEIN

Local NCS retraints between domains: 1 2

Local NCS retraints between domains: 3 4

Local NCS retraints between domains: 5 6