Crystal Structure of the P38a-MAPKAP kinase 2 Heterodimer

Crystal structure of the P38alpha-MAPKAP kinase 2 heterodimer.

Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAX-interacting protein 2, MAP kinase MXI2, SAPK2A

MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2

25% Peg 3350, 250 mM Sodium Formate, pH 7.2, VAPOR DIFFUSION, HANGING DROP, temperature 298K

This sequence occurs naturally in Homo sapiens (Humans)

Mitogen-activated protein kinase 14 (E.C.2.7.11.24), MAP kinase-activated protein kinase 2 (E.C.2.7.11.1)

Kinase, NLS, NES, heterodimer, docking groove, TRANSFERASE