InhA (T2A mutant) complexed with 4-((5-Amino-3-methyl-1H-pyrazol-1-yl)methyl)-N-(2-chloro-4-fluorobenzyl)benzamide

Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA.

Enoyl-[acyl-carrier-protein] reductase [NADH]

Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase

10% PEG6K, 0.1M Bicine pH9.
Cryo - well + 25% ethylene glycol

Enoyl-[acyl-carrier-protein] reductase [NADH] (E.C.1.3.1.9)

Inhibitor, complex, fragment based drug discovery, tuberculosis, OXIDOREDUCTASE