Crystal structure of Leptospira interrogans GAPDH

S-CYSTEINESULFINIC ACID; S-SULFINOCYSTEINE

The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity.

CHANNEL-CUT SI(111) + KB FOCUSING MIRRORS

Cys152 in chains A, B, C, D, F, G, and H has spontaneously oxidized to 3-sulfinoalanine (CSD).
Glyceraldehyde-3-phosphate dehydrogenase

Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

Elongated prisms with a dimension of 150-300 micromters in their longest axis

Spanish Ministry of Science, Innovation, and Universities

GAPDH, Leptospira interrogans, Immune evasion, Innate immunity, Complement system, HYDROLASE